Archive for the ‘GastroIntestinal / Gastroenterology’ Category
A UK-led international study has identified four types of genetic disturbance in the immune system that lead to celiac disease, bringing to 40 the total number of known inherited factors that increase a person's risk of developing the disease...
American Gastroenterological Association Leads The Way In GI Innovation
The American Gastroenterological Association (AGA) is taking the lead in gastroenterological innovation by conducting "Fostering Innovation and Technology in Digestive and Metabolic Diseases...
What Is Lactose Intolerance? What Causes Lactose Intolerance?
Lactose intolerance, also called lactase deficiency, occurs when the body cannot break down and absorb lactose. It is the inability to metabolize lactose because of a lack of the required enzyme lactase in the digestive system. A person with this problem is unable to fully digest the milk sugar (lactose) in dairy products. Lactose is a natural sugar that is found in milk...
Alkermes Announces Positive Results For Phase 1 Study Of New Drug Candidate For Treatment Of Opioid-Induced Constipation
Alkermes, Inc. (NASDAQ: ALKS) announced positive topline data from a phase 1 clinical study of ALKS 37, an orally active, peripherally-restricted opioid antagonist with potential to block the effects of opioid agonists on gastrointestinal motility, commonly referred to as opioid-induced constipation (OIC)...
Gastroenterology/Hepatology Societies Issue Recommendations On Nonanesthesiologist Administration Of Propofol For GI Endoscopy
The worldwide safety experience of endoscopist-administered propofol sedation now exceeds 600,000 patients...
Etiologic Factors Of Gastric Cardiac Adenocarcinoma Among Men In Taiwan
The gastric cardiac adenocarcinoma (GCA) is a very rare disease. In recent decades, however, the incidence of the GCA has increased dramatically in many Western countries. An increasing trend in GCA is also observed in municipal regions but not in rural regions of China. Another striking feature is the strong male predominance among patients with GCA...
Etiologic Factors Of Gastric Cardiac Adenocarcinoma Among Men In Taiwan
The gastric cardiac adenocarcinoma (GCA) is a very rare disease. In recent decades, however, the incidence of the GCA has increased dramatically in many Western countries. An increasing trend in GCA is also observed in municipal regions but not in rural regions of China. Another striking feature is the strong male predominance among patients with GCA...
First Effective Medical Therapy For Rare Stomach Disorder Reported By Vanderbilt Scientists
A drug used to treat colorectal cancer also can reverse a rare stomach disorder and should be considered first-line therapy for the disease, researchers at Vanderbilt University Medical Center report this week. Ménétrier's disease causes thickening of the stomach lining, severe abdominal pain, nausea and vomiting, as well as anemia and swelling in the feet and ankles due to protein loss...
Can EP4 Agonist Alleviate Gastric Lesions?
Over 300 million patients use non-steroidal anti-inflammatory drugs (NSAIDs) in the world to treat pain, arthritis, fever and other diseases. Nearly 30% of the users suffer from gastric lesions and bleeding. To mitigate NSAIDs' adverse effects on the stomach, misoprostol, a non-selective prostaglandin E1 (PGE1) analogue, has been prescribed as the first choice for prevention of NSAID-induced injuries, but often induces severe adverse effects.
Alkermes Announces Initiation Of Phase 1 Clinical Study Of ALKS 37 For The Treatment Of Opioid-Induced Constipation
Alkermes, Inc. (NASDAQ: ALKS) announced the initiation of a phase 1 clinical study of ALKS 37, an orally active, peripherally-restricted opioid antagonist with potential to block the opioid agonist effects on gastrointestinal motility, commonly referred to as opioid-induced constipation (OIC).
Patients Taking VIMOVO(TM) Showed A Decrease In Incidence Of NSAID-Associated Ulcers
AstraZeneca (NYSE: AZN) and POZEN Inc. (Nasdaq: POZN) announced pivotal data from two POZEN clinical trials that were presented at the American College of Rheumatology (ACR) 2009 Annual Scientific Meeting in Philadelphia, PA.
Children Can Greatly Reduce Abdominal Pain By Using Their Imagination: UNC Study
Children with functional abdominal pain who used audio recordings of guided imagery at home in addition to standard medical treatment were almost three times as likely to improve their pain problem, compared to children who received standard treatment alone. And those benefits were maintained six months after treatment ended, a new study by University of North Carolina at Chapel Hill and Duke University Medical Center researchers has found.
Gut Worms May Protect Against House-dust Mite Allergy
A study conducted in Vietnam has added further weight to the view that parasitic gut worms, such as hookworm, could help in the prevention and treatment of asthma and other allergies.
Gallbladder Emptying In Primary Sclerosing Cholangitis Patients
Primary sclerosing cholangitis (PSC) is an idiopathic chronic cholestatic inflammatory liver disease characterized by diffuse fibrosing inflammation of intra- and/or extrahepatic bile ducts, resulting in bile duct obliteration, biliary cirrhosis, and eventually hepatic failure. One of the most common symptoms at the time of presentation of PSC is mild to severe abdominal pain localized in the right upper quadrant.
Is Midline Or Transverse Incision Better For Abdominal Surgery?
An unusual study at the Department of Surgery at Heidelberg University Hospital examined for the first time whether the incision technique used in major abdominal surgery had an effect on the results. Neither physician nor patient knew what kind of incision had been made. The study of 200 patients showed that pain perception and the healing process were unrelated to the technique used to open the abdominal cavity.