Archive for the ‘Cancer / Oncology’ Category

Occupational Sunlight Exposure And Kidney Cancer Risk In Men

According to a new study, men employed in occupations with potential exposure to high levels of sunlight have a reduced risk of kidney cancer compared with men who were less likely to be exposed to sunlight at work. The study did not find an association between occupational sunlight exposure and kidney cancer risk in women...

Covidien Launches Oral Transmucosal Fentanyl Citrate Product

Covidien (NYSE: COV), a leading global provider of healthcare products, today announced that Mallinckrodt Inc., a Covidien company, has launched its Oral Transmucosal Fentanyl Citrate (CII) to distributors serving retail pharmacies across the country. The U.S...

Experts Call For Further Research Into The Relationship Between Insulin Therapy And Cancer

The benefits of using insulin to treat diabetes far outweigh the risks, but a review just published online by IJCP, the International Journal of Clinical Practice, suggests that commonly used diabetes therapies may differ from each other when it comes to their influence on cancer risk...

Hormone Thought To Slow Aging Associated With Increased Risk Of Cancer Death

According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), older men with high levels of the hormone IGF-I (insulin-like growth factor 1) are at increased risk of cancer death, independent of age, lifestyle and cancer history...

Hormone Thought To Slow Aging Associated With Increased Risk Of Cancer Death

According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), older men with high levels of the hormone IGF-I (insulin-like growth factor 1) are at increased risk of cancer death, independent of age, lifestyle and cancer history...

Inadequate Access To Opioid-Based Pain Relief Is A Human Rights Issue For Cancer Patients, Europe

Many cancer patients in Europe are being denied access to adequate pain relief because of over-zealous regulations restricting the availability and accessibility of opioid-based drugs such as morphine...

Orexo Announces Kyowa Hakko Kirin’s Submission Of KW-2246 (Abstral) For Approval In Japan

Orexo AB (STO:ORX) announces that its partner Kyowa Hakko Kirin Co., Ltd. has submitted the New Drug Application (NDA) in Japan for the cancer pain drug KW-2246 (Abstral). Kyowa Hakko Kirin has confirmed KW-2246's safety and efficacy in clinical trials conducted in Japan. The drug will be marketed by Kyowa Hakko Kirin and Hisamitsu Pharmaceutical Co., Inc...

New Round Of UREP Grants For WCMC-Q Students

Twenty-eight WCMC-Q students have received grants totaling $280,000 in the latest, seventh, round of funding from the Undergraduate Research Experience Program (UREP) to conduct advanced research projects with faculty members...

Testicular Cancer Diagnosis By Non-Invasive MRI

Researchers have found that non-invasive magnetic resonance imaging (MRI) is a good diagnostic tool for the evaluation and staging of testicular cancer and may improve patient care by sparing some men unnecessary surgery, according to a study in the March issue of the American Journal of Roentgenology (http://www.ajronline.org)...

Pediatric Cancer Survivors At Risk For Diseases That Predispose Them To Heart Disease

Survivors of pediatric cancer are at greater risk for high cholesterol, diabetes and high blood pressure, all of which predispose them to heart disease. These risk factors for heart disease are being found at an earlier age than in the general population, according to research published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research...

Radiofrequency Ablation Safe And Effective For Reducing Pain From Bone Metastases

Image-guided radiofrequency ablation (RFA), a minimally invasive cancer treatment which can be performed in the outpatient setting, significantly reduced the level of pain experienced by cancer patients with bone (osseous) metastases, limiting the need for strong narcotic pain management, and supporting improved patient frame of mind, according to results of an American College...

Insulin And Cancer Risk: Essential Considerations In The Investigation Of Associations

Epidemiological studies are difficult to do well, pharmacoepidemiological studies are particularly complicated and studies of insulin and cancer risk are even more difficult to do well. "Well" in the sense that any association found can be interpreted in an unambiguous manner...

The Need For Cardio-Oncology: Treating Cancer And Protecting The Heart

Cardiologists and oncologists must work together in an attempt to avoid or prevent adverse cardiovascular effects in patients from certain chemotherapies, especially for those who may be at a higher risk for such effects, according to a new review published online December 10 in the Journal of the National Cancer Institute...

Long-Term Testicular Cancer Survivors At High Risk For Neurological Side Effects

Long-term survivors of testicular cancer who were treated with cisplatin-based chemotherapy had more severe side effects, including neurological side effects and Raynaud-like phenomena, than men who were not treated with chemotherapy, according to a new study published online November 25 in the Journal of the National Cancer Institute. Marianne Brydøy, M.D...

Long-Term Testicular Cancer Survivors At High Risk For Neurological Side Effects

Long-term survivors of testicular cancer who were treated with cisplatin-based chemotherapy had more severe side effects, including neurological side effects and Raynaud-like phenomena, than men who were not treated with chemotherapy, according to a new study published online November 25 in the Journal of the National Cancer Institute. Marianne Brydøy, M.D...

Opiate Painkillers May Encourage Spread Of Cancer

New research from the US adds weight to the growing body of evidence that opiate-based painkillers like morphine, which has been used to treat postoperative and chronic cancer pain for two hundred years, encourage cancer cells to grow and spread...

Common Pain Relief Medication May Encourage Cancer Growth

Although morphine has been the gold-standard treatment for postoperative and chronic cancer pain for two centuries, a growing body of evidence is showing that opiate-based painkillers can stimulate the growth and spread of cancer cells. Two new studies advance that argument and demonstrate how shielding lung cancer cells from opiates reduces cell proliferation, invasion and migration in both cell-culture and mouse models.

Covidien Receives FDA Approval For Oral Transmucosal Fentanyl Citrate Product

Covidien (NYSE: COV), a leading global provider of healthcare products, announced that its subsidiary, Mallinckrodt Inc., has received U.S. Food and Drug Administration (FDA) approval of its Abbreviated New Drug Application (ANDA) for Oral Transmucosal Fentanyl Citrate (CII). Covidien's product is a generic alternative to the branded ACTIQ®. It is a solid formulation of fentanyl that resembles a lozenge on a handle.

Research Into Cancer During Pregnancy: Treating Pregnant Women With Chemotherapy Has No Detrimental Effect On The Foetus

Professor Frederic Amant of the Katholieke Universiteit Leuven (K.U.Leuven) directs research into the treatment of cancer in pregnant women and the consequences of such treatment on foetal development. In her PhD dissertation on chemotherapy during pregnancy, Kristel Van Calsteren presents new scientific discoveries. Kristel Van Calsteren has concluded that there is no increased risk of congenital defects in children who are exposed to chemotherapy during pregnancy.

Cancer Treatment During Pregnancy Need Not Risk Baby’s Health

Many women who discover they have cancer while pregnant risk their own health by postponing treatment. But an international collaborative study carried out in Belgium, the Netherlands and the Czech Republic, has shown that, while babies born to women who undergo cytotoxic treatment during pregnancy tend to be born prematurely and are small for gestational age, most achieve a good outcome and the incidence of congenital malformations is comparable to the general population.

Plexxikon Treats Initial Patient With First-in-Class Drug In Phase 1 Trial

Plexxikon Inc. today announced that dosing of cancer patients with PLX3397 has started in a Phase 1 clinical trial. PLX3397 is a novel, oral investigational drug for treating multiple diseases, including metastatic cancer and rheumatoid arthritis. PLX3397 is a highly selective kinase inhibitor that down-modulates macrophages, osteoclasts and mast cells-all cells derived from the immune system-as well as certain tumor cells that promote tumor growth and metastases to the bone.